A man has died and another is in a serious condition after a gas leak at a Carlsberg factory, the brewer said.
Emergency services were called to the brewery in Northampton town centre at 12.30pm following reports of an industrial accident.
A total of 22 people - 11 staff, two police officers and nine firefighters - were taken to hospital.
Northamptonshire Police said a man in his 40s had died.
A 51-year-old man who was working at the site remains in a serious but stable condition, Carlsberg confirmed.
Julian Momen, chief executive officer, Carlsberg UK, said on Wednesday evening: "We are deeply, deeply saddened by today's tragic incident and subsequent fatality.
"Our immediate thoughts are with the individual's family, friends and colleagues at this very difficult time and we will support them in every way we can.
"Our further thoughts and support are with our colleagues and members of the emergency services who are being treated in hospital.
"One of our colleagues remains in a serious but stable condition. Nothing is more important to us than the safety of everyone working for us.
"We are working closely with the authorities to investigate how this tragic incident occurred and we will be in a position to say more once a full investigation has been concluded."
A police spokesman said: "Other staff from Carlsberg and emergency service personnel remain at the hospital receiving treatment.
"Northamptonshire Police are working with the Health and Safety Executive to investigate the incident."
The gas leak was confined to the factory site and there is not thought to be a wider risk to members of the public.