Some Apple services, including iTunes, the App Store and the firm's new Apple Music are down for some users.
Reports of problems across a host of services, also including Apple TV and the iBooks store, have been logged by the technology giant, with the iPhone maker saying it is investigating the problems.
In a note on the firm's official System Status page which flagged the troubled services, Apple said it will "update the status as more information becomes available".
The reported outage for some users came at a particularly unfortunate time for the company, as its Beats 1 radio station had just announced the nominees for the MTV Video Music Awards (VMAs), which it was doing exclusively. Beats 1 only launched as part of Apple Music last month, and the radio station also has the tagline "Worldwide. Always on."
A range of other iTunes services, including iTunes in the Cloud, Match and iTunes U are also listed as experiencing issues, as well as the Mac App Store, OS X Software Updates, Radio and the Volume Purchase Programme.
All other services - including Beats Music - are said to be working normally.