Oprah Winfrey's Lance Armstrong Interview Tops 'Confessionals' With Tom Cruise, Marion Jones & Whitney Houston

Five Other Oprah Winfrey Interviews That Were A Big Deal
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Oprah Winfrey's interview with disgraced cyclist Lance Armstrong crowns a lengthy career of coaxing confessionals from celebrities.

The talk-show host, who secured an exclusive interview with Armstrong in the wake of his doping scandal, has often lent a sympathetic ear to a public face during the various incarnations of her show and persona.

She later told CBS This Morning the interview with Armstrong had been the "biggest" of her entire career.

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A shoulder to cry on: Oprah Winfrey

Jones wept three times and read out a letter she'd written to her children from prison. She said: "Oprah, I didn't love myself enough to tell the truth."

Oprah also played an instrumental part in Ellen DeGeneres' "coming out" live on TV in 1997. Winfrey played the part of a therapist who helped DeGeneres realise she was gay during the "puppy" episode of her namesake show.

Most recently Oprah has provided a shoulder to cry on for fellow talk-show host David Letterman. The pair discussed everything from his depression to his sex scandal in 2009.