Sheridan Smith will not perform at this year's Royal Variety Performance following the death of her father, Colin, this week.
The Funny Girl star was due to perform alongside other celebrities such as Sting and Robbie Williams in the show, which will take place in front of the Prince of Wales and the Duchess of Cornwall.
A statement said: "Sheridan's much loved father sadly passed away this week.
"We can confirm that she will not be performing at the Royal Variety Performance this Tuesday.
"At this difficult time for Sheridan and her family we would ask that you please respect their privacy."
Smith, 35, revealed in March this year that her father had been diagnosed with cancer. Following the news, she pulled out of a performance of the West End musical, Funny Girl.
She shared the news with her Twitter followers writing: "Had shit news 2day, sorry I can't make the show for u loyal fans, if u ask they give u tix to the Savoy!''
She added: ''it's one, hate missing shows but pappa needs me x''
The actress's eldest brother Julian died from cancer at the age of 18.
Smith starred in the BBC1 drama, The C Word, last year which saw her portraying blogger Lisa Lynch.
The film documented Ms Lynch's battle with cancer and was based on her blog - named Alright Tit - and a book which was born out of the blog.
Smith's parents - Colin and Marilyn - formed the Country and Western duo, The Daltons.
The band's Facebook page describes their sound as being inspired by the work of Johnny Cash, Hank Williams and Dolly Parton.
A young Sheridan often performed with her parents, and her brother Damian, who is part of the band The Torn, also often joined his parents on stage.
In an interview with The Telegraph in 2010, Smith described her family as being "a bit like The Waltons".
She said: "My parents are a Country and Western duo called The Daltons. They used to perform seven nights a week and when I was four I joined them on stage doing little dance routines. It wasn't long before I was standing on a stool joining in the singing.
"They don't often have gigs at weekends now but if they do I'll be there joining in. I love to perform. But these days it's more likely we'll all go to support my brother Damian's gig. He is a guitarist in the band Torn."
The Royal Variety Performance is staged in aid of the Royal Variety Charity, formerly the Entertainment Artistes' Benevolent Fund, of which the Queen is patron.
This year's show will be hosted by David Walliams and has other big names such as Gary Barlow, Emeli Sande and Britain's Got Talent winner and magician Lance Corporal Richard Jones on the bill.
The cast of Cirque du Soleil's The Beatles Love show will fly over from Las Vegas for a special performance to mark its 10th anniversary.
The money raised from the Royal Variety Performance helps people from the world of entertainment in need of care and assistance.
It will take place at the Eventim Apollo in Hammersmith on December 6 and will be broadcast on ITV.