Celebrity Big Brother contestants Marnie Simpson, Renee Graziano, James Whale and Stephen Bear have been nominated for eviction.
Simpson, Graziano and Whale were chosen by the housemates saved by the last public vote to face eviction in so-called "killer nominations", which were delivered face-to-face in Wednesday night's episode.
Ex On The Beach star Bear, who escaped the boot on Tuesday, opted for Graziano, saying: "I'm not being funny, very negative."
After her nomination, Graziano said: "I've got a mouth sharper than a motherf****** sword. I don't want to hug anybody. This is not so serious, I get to go home to my kids. That boy, at home, would roof my house."
The Only Way Is Essex star Lewis Bloor chose Whale, saying: "I believe he's a threat in the house and is doing very well in here. He's a very capable housemate and if he's not put up for nomination could go all the way."
Storage Hunters UK star Heavy D chose Geordie Shore star Simpson, saying: "I don't think you're a nice person. I don't like you."
Bear will face the public vote every week because he has an external nomination.
During the episode housemates have been shocked, handcuffed, blindfolded and smeared with custard pies in a bid to win the latest task.
In a game of dares Ricky Norwood, Frankie Grandie and Whale strapped shock pads to their bottoms and were hit by currents.
Saira Khan, who was evicted on Tuesday night, Bloor and Heavy D were handcuffed together and Katie Waissel, Samantha Fox and Simpson were dared to throw custard pies at their fellow housemates.
Aubrey O'Day, Graziano and Chloe Khan were dared to eat a buffet blindfolded but Mob Wives star Graziano refused.
The romance between Bloor and Simpson continues to escalate in the episode, with the pair seen cosying up in the shower shortly after Khan's eviction.
Later in the episode, housemates were shocked when Chloe Khan performed a topless pole dance before throwing cake with Bear, Simpson and Bloor in the bedroom, prompting Whale, Fox, O'Day, Grande, Waissel and Norwood to threaten to leave.
In the diary room with the group, Whale said: "We can't go on like this ... we all want to leave. There are four protagonists and they have overstepped the line tonight.
"This could be the first strike in the history of Big Brother and I'm very right wing!"
At the end of the episode it was revealed that the nominated housemates will have a chance to save themselves from the chopping block in Thursday's show.
:: Celebrity Big Brother is on Channel 5 at 9pm.