You feel cranky, confused and, given half the chance, you could probably sleep for days.
While it's difficult to recover from jet lag, there are a handful of preventative measures you can take to ensure that your travels start and end in the best way possible.
And seeing as it can affect all manner of bodily functions including: appetite, digestion, bowel habits, urine production, body temperature and blood pressure, it's worth limiting the amount of potential damage beforehand, right?
Whether you're preparing your body for the zone change by gradually shifting your schedule later each day, or opting to fly at night (and in doing so, allowing your body the best chance to rest up) - these small steps will no doubt save you from those feelings of grumpiness, lethargy and general irritability once you get to the other side.
And if, once you arrive at your destination, you're still worried about suffering from jet lag then let these wise words from health advisors at NHS Choices guide you:
Firstly, establish a new routine. You can do this by eating and sleeping at the correct times for your new time zone, rather than the time you usually eat and sleep at home.
Next up, avoid having a nap as soon as you arrive. Even if you're tired after a long flight, staying active until your new bedtime will help your body adjust quicker.
And finally, spend time outdoors as natural light (hello sunshine!) will help your body adjust to a new routine.
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[H/T Daily Mail]