A bridge has collapsed and roads have been closed, leaving motorists stranded as rivers in the Yorkshire Dales burst their banks.
The region is braced for weather conditions to worsen as the Met Office has issued a yellow warning for rain for much of the north of England.
North Yorkshire was pounded on Tuesday by hailstones as a summer storm swept through the county, while Malham Tarn in the Yorkshire Dales had 82.2mm of rain in 24 hours, the majority in the space of four hours.
The monthly average in the area for this time of year is 89mm.
The River Swale and the River Dee both burst their banks in the area, making some roads completely impassable.
Video footage shows fast flowing and dangerous conditions between Cogden Beck and Grinton, while the road appears to have eroded on the B6270 between Grinton and Downhome.
Mountain rescue teams, North Yorkshire Police and the fire service had to come to the aide of stranded motorists in the Dales on Tuesday night.
North Yorkshire Fire and Rescue Service said it received around 115 calls to flooding incidents in Leyburn and Reeth on Tuesday evening.
A spokesman said: “We had several appliances, as well as our swift water rescue teams and high volume pumping appliance within the area attending various incidents involving flooded properties and cars stuck in flood water.”
Train passengers faced disruption after a landslip between Carlisle and Skipton.
Northern Rail said trains had been suspended between Ribblehead and Kirkby Stephen.
The Environment Agency has issued a fresh flood warning for the area due to “intense downpours” which will cause river levels to to rise significantly overnight.
Other parts of Britain could face “persistent and heavy” rain on Wednesday with the Met Office warning storms could dump up to 40mm of rain in two hours in places.
A yellow weather warning for rain has been issued for parts of central and northern England, while a similar alert for thunderstorms is in place in Scotland.
There are 10 flood warnings in place across the UK – from North Yorkshire, Lancashire and the West Midlands – with the Environment Agency saying local flooding was possible due to the thunderstorms and outbreaks of heavy rain.
The Met Office said: “Rain will be persistent and heavy in places across parts of central, northern and eastern England and north-east Wales at first on Wednesday.
“During the day rain may turn more showery in places but with a higher chance of thunderstorms by afternoon.
“Some parts of northern England could see as much as 40-60mm of rain through Wednesday, while thunderstorms could produce as much as 30-40 mm in 1-2 hours.”
The unsettled weather is a continuation of Tuesday, where hailstones the size of sweets fell in some areas and others having a month’s worth of rain in four hours.