Johnny Depp
The Wednesday star was quick to shut down the "ridiculous" rumours last year.
People are already calling out the "distasteful" jab, made by Hannah Waddingham's character.
A sixth film in the hugely popular Disney series is officially in the works.
Glaudini said the memory came flooding back after watching Amber Heard testify against Depp during his 2022 defamation trial.
"I want to address what is one of the most thoughtless, insensitive, and ignorant things I’ve ever done,” she wrote on Instagram.
“Mr. Depp has no personal or professional relationship with Ms. Ortega whatsoever,” his rep said.
The Wednesday actor responded to the claims on her Instagram story.
The docuseries Depp v. Heard is slated to hit the streaming service next month.
Meanwhile, Mary's co-star Jane Fonda also acknowledged getting hot and bothered with someone on camera.
The Aquaman actor moved abroad after a highly publicised defamation trial with ex-husband Johnny Depp.