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The rapper and actor had made comments about Madonna's recent bedroom photoshoot.
The Queen of Pop then turned the tables on her tattoo artist after getting inked for the third time.
"Giving thanks that I have managed to maintain my sanity through four decades of censorship, sexism, ageism and misogyny."
It's fair to say Madonna's latest Instagram post received quite the mixed reception.
“I needed to be completely independent from her as soon as I graduated high school.”
When the host pointed out Madonna's knack for getting into "good trouble", she couldn't resist taking him on his word.
Even Marge Simpson has stripped to her birthday suit for the iconic magazine.
The singer is the latest star to speak out in support of Britney.
He's insisted the singer didn't mean to be negative with the remark she posted on her Instagram.
The singer raised eyebrows after an Instagram post about Lil Nas X's recent performance.